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December 2022 COVID-19 Vaccination Update Supplemental Information

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December 2022 COVID-19 Vaccination Update Supplemental Information

Interim Clinical Considerations for Use of COVID-19 Vaccines Currently Approved or Authorized in the United States




Bivalent Booster Studies


Here is a good summary of the studies:




Bivalent vaccines versus BQ Variants


mRNA bivalent booster enhances neutralization against BA.2.75.2 and BQ.1.1



Improved Neutralization of Omicron BA.4/5, BA.4.6, BA.2.75.2, BQ.1.1, and XBB.1 with Bivalent BA.4/5 Vaccine



Low neutralization of SARS-CoV-2 Omicron BA.2.75.2, BQ.1.1, and XBB.1 by parental mRNA vaccine or a BA.5-bivalent booster




The BQ.1.1 variant story




As COVID-19 cases climb, experts stress importance of getting your shot



Information on variants



A brief summary of how the immune system works:


Can You Boost Your Immune System?



How a virus enters a cell (video made 5 years ago):


Animation of steps that occur when SARS-CoV-2 enters a cell:


How mRNA vaccines work with the immune system:



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